Research Sees MS Reversal In Mice

Researchers in Montreal, Canada has reported on finding an experimental treatment that may soon change the way multiple sclerosis may be treated. The said finding has seen a reversal of the disorder in a mouse model. The researchers believe that the same thing might likely happen to humans as well.

The new treatment known as GIFT15, puts multiple sclerosis in remission by suppressing the immune response. Multiple sclerosis is an autoimmune disease characterized by the body’s immune system mounting an attack on the body’s own central nervous system, causing several progressive physical and cognitive disabilities.

GIFT15 is composed of two proteins fused together artificially that creates a quite unexpected biological effect. It converts B-cells into immune suppressive cells. When injected into a mice model of multiple sclerosis, the researchers saw that the disease seem to go away. The researchers also noted no significant side effects on the mice it injected with GIFT15.

The researchers, led by Dr. Jacques Galipeau of the Jewish General Hospital Lady Davis Institute for Medical Research and McGill University, still cautioned that the said study may still be in its preliminary stage and may require further investigation. "We do need to note that what is demonstrated in animal models may not be replicated in people and this research does not relate to studies in humans at this point in time," added spokesman Jon Temme.

The study does give credence to the belief of multiple approaches that researchers try to investigate in order to find a successful treatment for the disease. Initial research may also suggest of GIFT15 being effective as treatment for other autoimmune diseases that may affect humans.


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