Research Finds Link Between Glandular Fever And MS

A study made by researchers from the Australian National University may have found a link between glandular fever and multiple sclerosis. The new study reported findings that people who have glandular fever antibodies also have a much greater risk of developing multiple sclerosis later on. The research findings are published in the journal Neurology.

Robyn Lucas, ANU Associate Professor and author of the said study, evaluated 300 participants with MS and another 500 healthy participants along with a team of researchers. The team found out that those of the participants who had antibodies as a result of a past case of glandular disease or of EBV (Epstein-Barr Virus) were of higher likelihood to develop MS. The researchers also found out that other genetic changes associated with the immune system also added to the risk of developing MS.

According to Associate Prof. Lucas, “We found that the presence of EBV antibodies was directly related to an increased risk of demyelinating disease, and there was also a strong relationship with certain genes of central importance to the immune system.”

“High levels of EBV antibodies indicate a past infection with glandular fever, which in combination with a specific HLA-DR15 or HLA-A genotype increased the risk of a first demyelinating event by 20 times,” Associate Prof. Lucas further added. The results of the said research was consistent with other studies that also showed a link between past EBV infection with MS risk.


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