Reason Why MS Is Affecting More Women Found

A recent study reveal a probable reason why women tend to get affected more by multiple sclerosis than men. It seems that women are more susceptible to MS because of a gene associated with disease that is passed on to more women than in men. The findings of the said study is published in the January issue of the online journal Neurology.

The said research has shown that people afflicted with MS has been rising among women. Although the actual cause of the disease is not yet known, environmental factors seem to play a role. The study also showed that a certain gene known as the human leukocyte antigen or HLA class II gene may make people genetically susceptible to the disease.

The study involved studying and examining the genes of 1,055 families with more than one family member afflicted with MS. The genes of 7,093 people were tested, of which 2,127 had MS. The researchers also looked at the HLA genes in people with or without MS and from which part of the family the genes were inherited from.

The study results showed that women who had MS were 1.5 times were more likely to have an HLA gene variant that is susceptible to MS compared to men with MS.

According to George C. Ebers, MD, FMedSCi, from the University of Oxford in the United Kingdom and the study author, “Our findings also show women with the HLA gene variant are more likely to transmit the gene variant to other women in their families than to men.”

The study also has shown that second degree relatives are more likely to inherit the gene variant associated with MS than first degree relatives.

Source: American Academy of Neurology. “Women with multiple sclerosis more likely to have MS-related gene than men.” ScienceDaily 6 January 2011. 11 January 2011 <http://www.sciencedaily.comĀ­ /releases/2011/01/110105194832.htm>

 
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