High Doses Of Vitamin D Not Any Better Than Low Dosages For MS

A new study has found out that getting high dosage of vitamin D may not provide any beneficial effects for MS patients better than what a low dose of vitamin D already can provide. This issue has been up for debate for quite awhile now and how low vitamin D levels have been associated with increased MS risk. The study findings are published in the October 25 issue of Neurology, the medical journal of the American Academy of Neurology.

The study involved 23 people suffering from a relapsing-remitting form of MS. Half of the participants were either given a high dose of vitamin D2 to elevate their blood vitamin D levels or a placebo. All of the participants were given low dose vitamin D supplements to make sure that there is no vitamin D deficiency during the course of the 6 month study.

As part of the study, the participants had their MRI scans taken at the study onset and again during the fourth, fifth and sixth months of the said study. The researchers then analyzed the results and saw no significant difference between the two groups when it comes to the number of new abnormalities formed in the brain after six months. There was also no significant difference seen in the total volume of abnormalities found in both groups.

In addition, 4 of the 11 participants who took the high dose vitamin D experienced a relapse of MS where the symptoms worsened during the study. In contrast, none of the 12 participants taking the low-dose vitamin D experience any relapse of the said disease.

According to Mark S. Stein, MBBS, PhD, FRACP of The Royal Melbourne Hospital and The Walter and Eliza Hall Institute of Medical Research in Parkville, Australia said, “We did not find added benefit from high-dose vitamin D over and above ongoing low-dose vitamin D supplementation, but these results need to be confirmed with larger studies.”

But Dr. Stein also noted that the study involved participants who have been suffering from Ms for an average period of 6 years. “It’s possible that studies of high-dose vitamin D at an earlier stage of MS may lead to different results,” he further added.

Source: American Academy of Neurology (2011, October 24). High-dose vitamin D may not be better than low-dose vitamin D in treating multiple sclerosis. ScienceDaily. Retrieved October 25, 2011, from http://www.sciencedaily.com/releases/2011/10/111024164701.htm

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One Response to “High Doses Of Vitamin D Not Any Better Than Low Dosages For MS”

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